Постнатальное развитие комплекса заднелатеральных ядер дорзального таламуса

Авторы

  • Наталья Сергеевна Меркульева Институт физиологии им. И. П. Павлова РАН; Санкт-Петербургский государственный университет https://orcid.org/0000-0003-1276-1918
  • Александр Александрович Михалкин Институт физиологии им. И. П. Павлова РАН https://orcid.org/0000-0003-2342-6357
  • Нина Ивановна Никитина Институт физиологии им. И. П. Павлова РАН

DOI:

https://doi.org/10.33910/2687-1270-2020-1-3-242-248

Ключевые слова:

комплекс LP-pulvinar, ранний постнатальный онтогенез, ацетилхолинэстераза, временное мечение, кошка

Аннотация

С помощью метода гистохимической визуализации ацетилхолинэстеразы (АХЭ) изучено постнатальное развитие комплекса заднелатеральных ядер и подушки (LP-pulvinar) кошки. У животных возраста 4–21 дня в латеральном ядре комплекса выявлено кластерное распределение АХЭ в нейропиле. Средний размер АХЭ кластеров и расстояние между их центрами составили 200–300 мкм и 430–600 мкм соответственно. Оптический контраст кластеров быстро нарастал в период между 4-м и 14-м постнатальным днем, достигая максимального значения, после чего быстро снижался, достигая минимальных значений у животных возраста 21 дней. Поскольку АХЭ напрямую связана с нейрональной дифференцировкой и развитием, а АХЭ кластеры локализуются в той же области, что и нейроны, организующие таламокорковые связи, полагаем, что последние могут быть функционально связаны с развитием зрительных модулей.

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30.09.2020

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